Dr. David W. Britt

Assistant Professor, Department of Biological Engineering

Degrees

• Max Planck Institute, Göttingen Thin films / high res. microscopy Post-Doc 1998 - 2000
• University of Utah Bioengineering Ph.D. 1998
• University of Puerto Rico Spanish minor 1989 -1990
• University of Utah Chemistry / Materials Sci. & Eng. B.S. 1992

Academic Honors and Awards

• Outstanding Teacher, Department of Biological Engineering, Utah State University (2003-2004)
• Outstanding Advisor, Department of Biological Engineering, Utah State University (2002-2003)
• Ph.D. dissertation nominated to represent the University of Utah for the 2000 Council of Graduate Schools International Distinguished Dissertation Award in the Physical Sciences, Mathematics, and Engineering
• Cover of the journal Langmuir (vol. 17, June 12, 2001)
• National Science Foundation-NATO Post-Doctoral Fellow (1998 - 1999)
• Whitaker Bio-Based Engineering Fellow (1995 - 1996)
• University of Utah Graduate Research Fellow (1995 - 1996)
• Becton Dickinson Service Learning Scholar (1994)
• NIH Training Grant Fellow (1993 - 1994)

Teaching Experience

• (BIE 6930) Special Studies in Interfacial Science and Engineering* (trial offering, spring, 2004)
• (BIE 5850 / 6850) Biomaterials Engineering* (yearly since 2002, will offer alternate years w/ 6930)
• (BIE 2330) Properties of Biomaterials* (yearly since 2002)
• (BIE 3000) Bioinstrumentation* (2003, 2004)
• (BIE 3870) Junior Design (2003)
• (BioMed Eng 6040) Introduction to Biomaterials (Univ. Utah, 2001)
• (BioMed Eng 3101) Undergraduate Biomedical Engineering Laboratory* (Univ. Utah, 2001)

Professional / Honor Societies

• Materials Research Society. Institute for Biological Engineers. American Chemical Society
• Phi Beta Kappa Honor Society. Tau Beta Pi Engineering Society

Graduate Students (1 Ph.D., 5 M.S.) (* = graduated 2004)

Ph.D. : R. Pepalla

M.S. : G. Narasimham, H. Dhruv; M. Taveras, B. Madsen, M. Draper*

Publications :

• Du, X., V. Hlady, D.W. Britt, Langmuir Monolayer Approaches to Protein Recognition through Molecular Imprinting, Accepted to Biosensors and Bioelectronics, September, 2004.
• Goodman, T., E. Bussmann, C. Williams, M. Taveras, D. Britt, Miscibility analysis of two-component lipid monolayers using electrostatic force microscopy, Langmuir, 20, 3684-3689, 2004.
• Britt, D.W., T. Goodman, C. Selle, The Influence of Lipid Dipole Moment and Interfacial Water Structure on Protein Adsorption to Mixed Lipid Monolayers, Materialwissenschaft & Werkstofftechnik, 34, 1133-1137, 2003.
• Britt, D.W., G. Jogikalmath and V. Hlady, Protein Interactions with Monolayers at the Air/Water Interface, "Biopolymers at Interfaces" 2nd Ed, M. Malmsten, Ed. M. Dekker, Inc. 415-434, 2003
• Britt, D.W., U. Hoffmann, D. Möbius and S. Hell, Influence of Substrate Properties on the Topochemical Polymerization of Diacetylene Monolayers, Langmuir, 17, 3757-3765, 2001.
• Britt, D.W., V. Hlady and D. Möbius, Ferritin Adsorption to Multicomponent Monolayers: Influence of Lipid Charge Density, Miscibility and Fluidity on Adsorption, Phys. Chem. Chem. Phys., 2, 4594-4599, 2000.
• Hlady, V., C.-H. Ho and D.W. Britt, Quantitative Analysis of Protein Adsorption Kinetics, in "Interfacial Dynamics" N. Kallay, Ed., Surfactant Science Series, M. Dekker Inc., NY, pp. 405-418, 2000.
• Britt, D.W. and V. Hlady, Separating Octadecyltrimethoxysilane Hydrolysis from Condensation at the Air/Water Interface through Addition of Methyl Stearate, J. Phys. Chem. B., 103, 2749-2754,1999.
• Britt, D.W., and V. Hlady, Protonation, Hydrolysis and Condensation of Mono- and Tri-functional Silanes at the Air/Water Interface, Langmuir, 15, 1770-1776,1999.
• Britt, D.W., Alkyl-Silane Monolayers for Protein and Virus Adsorption Studies. Ph.D. thesis, University of Utah, Department of Bioengineering, 1998.
• Buijs, J., D.W. Britt and V. Hlady, Human Growth Hormone Adsorption Kinetics and Conformation on Self-Assembled Monolayers. Langmuir, 14, 335-341, 1998.
• Britt, D.W., Jos Buijs and V. Hlady, TMV Adsorption on Self-Assembled and Langmuir-Blodgett Monolayers Studied by TIRF and SFM. Thin Solid Films, 327-329, 824-828, 1998.
• Britt, D.W. and V. Hlady, In-Situ AFM Imaging of Calcite Etch Pit Morphology Changes in Undersaturated and HEDP-Poisoned Solutions. Langmuir, 13, 1873-1876, 1997.
• Britt, D.W. and V. Hlady, An AFM Study of the Effects of Silanization Temperature, Hydration and Annealing on the Nucleation and Aggregation of Condensed OTS Domains on Mica. J. Colloid Interface Sci., 178, 775-784, 1996.
• Ho, Chih-Hu, D.W. Britt and V. Hlady, Human Low Density Lipoprotein and Human Serum Albumin Adsorption onto Model Surfaces Studied by Total Internal Reflection Fluorescence and Scanning Force Microscopy. J. Molec. Recognition, 9, 444-455, 1996.

Scientific Presentations, Invited Lectures, and Conference Proceedings

• Dhruv, H., M. Draper, D. Britt. Self-Assembly Approaches to Organogel Construction. Accepted for presentation at the Materials Research Society Fall Meeting, Boston, MA, Nov 29 – Dec 3, 2004.
• Narasimhan, G., J. Johnson, A. Rodriguez, A.J. Anderson, D.W. Britt. Physicochemical parameters influencing the formation of biofilms compared in mutant and wild type cells of Pseudomonas chlororaphis O6. IWA International Conference Biofilms 2004: Structure and Activity of Biofilms. Las Vegas, NV, October 24 – 26, 2004.
• Hall, H., S. Mann, G. Narasimhan, A.J. Anderson, D.W. Britt. Pluronics® modify bacterial traits in a pseudomonad. IWA International Conference Biofilms 2004: Structure and Activity of Biofilms. Las Vegas, NV, October 24 – 26, 2004.
• Nickolov, Z.S., D.W. Britt, J.D. Miller. Sum-Frequency Spectroscopic Study of the Stearic Acid Monolayer – Water Interface. 78th American Chemical Society Colloid and Surface Science Symposium, Yale University, New Haven, CT, June 20 – 23, 2004.
• Britt, D.W., E. Bussmann, C. Williams. Surfactant Miscibility Analysis with Electrostatic Force Microscopy. 78th American Chemical Society Colloid and Surface Science Symposium, Yale University, New Haven, CT, June 20 – 23, 2004.
• Narasimhan, G., J. Johnson, B. Esplin, A.J. Anderson, and D.W. Britt. Atomic Force Microscopy Adhesion Mapping of Bacterial Biofilms. American Association for the Advancement of Science (Pacific Division) Conference, Utah State University, June 13-17, 2004.
• Hall, H., S. Mann, B. Esplin, A.J. Anderson, and D.W. Britt. Influence of Pluronics on Planktonic and Biofilm Growth of a Soil Bacterium. American Association for the Advancement of Science (Pacific Division) Conference, Utah State University, June 13-17, 2004.
• Nickolov, Z., J. Miller, V. Hlady, H. Patel, D. Britt, Two-Dimensional Sol-Gel Molecular Imprinting for Protein Recognition, The Eighth World Congress on Biosensors, Granada, Spain, May 24-26, 2004.
• Dhruv, H., D. Britt, Water Contact Angle and Atomic Force Microscopy Analysis of Caseinate Thin Films, 2004 Proceedings of the Institute of Biological Engineering, Fayetteville, Arkansas, January 8-10, 2004.
• Liang, Y., C. Miller, D. Britt, R. Sims, Effect of Humic Acid on Pyrene Degradation, Posters on the Hill, Salt Lake City, Utah, October 6, 2003.
• Nickolov, Z. S., J. D. Miller, D. W. Britt, Studies of Mixed Surfactant Monolayers at Interfaces by Sum Frequency Spectroscopy, XXXIII Colloquium Spectroscopicum Internationale, Granada, Spain, September 7-12, 2003.
• Fox, C., D. Britt, Pluronic Adsorption, Distribution and Stability. 17th National Conference on Undergraduate Research, University of Utah, March 13-15, 2003.
• Britt, D. Influence of surface dipoles on protein adsorption to membranes. Invited lecture to the University of Utah Departments of Metallurgy and Materials Science and Engineering, March 12, 2003.
• Britt, D.W., V. Deshmuk, V. Hlady, Protein Interactions with Heterogeneous Surfaces. Invited lecture at the 5th International Essen Symposium on Biomaterials. Essen, Germany, October 9-11, 2002.
• Hlady, V., D.W. Britt, G. Jogikalmath, Protein Adsorption at the Air / Water Interface. Presented at the 223rd National American Chemical Society Meeting. Orlando, FL, April 7-11, 2002.
• Britt, D.W., C. Selle, M. Lösche, S. Hell and D. Möbius, Lipid miscibility and excess surface potentials in mixed monolayers of cationic and neutral lipids. Presented at the University of Washington 5th Summer Symposium, Seattle, Washington, Aug. 19-21, 2001.
• Britt, D.W.,, Adsorption and Entrapment of Proteins in Alkylsilane and Mixed Lipid Monolayers. Invited lecture for the "Molecules in Interaction with Interfaces" Sonderforschungsbereich seminar 294 presented at the University of Leipzig. Leipzig, Germany, April 26, 2000.
• Britt, D.W., V. Hlady and D. Möbius, Influence of Monolayer Charge Density on Ferritin Adsorption Kinetics. Presented at the Interactions of Biopolymers with Model Membranes International Bunsen Discussion Meeting. Halle, Germany, March 2000.
• Britt, D.W., and V. Hlady, Virus Adsorption on Self-Assembled and Langmuir-Blodgett Monolayers. Presented at the Eighth International Conference on Organized Molecular Films. Asilomar, CA, August, 1997.
• Britt, D.W.,, Jos Buijs, and V. Hlady, Virus Adsorption at Self Assembled Monolayer and Model Lipid Interfaces. Presented at the 213th National Meeting of the American Chemical Society. San Francisco, CA, April, 1997.

Current Research Grants

• Improving water infiltration and retention in irrigated soil treated with biodegradable lactose-based wetting agents. D.W. Britt (P.I.) Community/University Research Initiative Grant. May 1, 2004 – June 30, 2005. $19,000
• Re-Defining Biological Engineering in an Integrated Research and Cooperative based Undergraduate Curriculum. D.W. Britt (P.I.), T. Taylor (Co. P.I.), K.T. Nguyen (Co. P.I.), National Science Foundation, September 1, 2004 – July 30, 2005. $100,000
• Two-Dimensional Sol-Gel Protein Imprinting, D.W. Britt (P.I.), J. Miller (Co. P.I.), V. Hlady (Co. P.I.) National Science Foundation, July 01, 2004 – June 30, 2005. $100,000