Dr.
Linda S. Powers Dr.
Linda S. Powers
The research efforts of this center are both basic and applied. Accordingly, the expertise of chemists, microbiologists, biochemists, physicists, and engineers (biological, computer, electrical, environmental , and mechanical) is brought to bear on problems falling within three broad categories: establishing the underlying basis for the design of biomolecular function, the development of novel spectroscopic and kinetic instrumentation, and engineering applications of biotechnology to environmental and biomedical problems. The NCDMF photonics laboratory possesses a variety of capabilities, including photothermal, transient, and real-time time-resolved absorption/ emission measurements. This facility includes a large, shielded laser enclosure containing two excimer lasers, a copper vapor laser (300 kW peak power), and three dye lasers with >10% energy conversion efficiency . A broad selection of optical and diagnostic equipment is available, including four optical tables, and a CCD detector. The biochemical laboratory contains space sufficient a dozen personnel, and is stocked with an extensive complement of reagents and supplies. A cold room and a dark room are located adjacent to a large preparations laboratory. A nearby instrumentation room houses cell sorting instruments, a dual-wavelength double-beam spectrophotometer, a custom-built stopped-flow spectrophotometer, a temperature-jump apparatus, and a computer-interfaced electron spin resonance spectrometer equipped for studying reactions having msec time resolution. A Sun computer system with high resolution graphics terminals coupled to a bank of i860 transputer parallel processing nodes provide nearly a GFLOP of computing power for 3-D molecular graphics and molecular dynamics calculations as well as other parallel applications .
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L.Bubacco, R. Magliozzo, M. Wirt, J.Peisach, and L.Powers: Heterotropic Effects of the Active Site Structure of Hemocyanin Detected by X-ray Spectroscopy, Biochen.
M. Chen, R.Sinclair, S. Hallam, S.Sligar, and L.Powers : Axial Ligand Substitution in Sperm Whale Myoglobin: Biochemical Characterization and Heme Structure, Biochim. Biophys.Acta
L. Powers and M. A. Griep, Escherichia coli Primase Zinc Is Sensitive to Substrate and Cofactor Binding, Biochem. 38, 7413 (1999)
1966 Westinghouse Science Talent Search (5th Place National Competiona)
1966 Ford Future Scientists of America (National Winner)
1966 West Virginia Science Talent Search (1st Place)
1969 Secretary Student Body, Virginia Polytechnic Institute and State University
1970 Sigma Pi Sigma
1970 Phi Lambda Upsilon
1982 First U.S. Bioenergetics Award, Biophysical Society
1983 Fellow, American Physical Society
1987 Fellow, American Institute of Chemists
1992 Watkins Visiting Professor in the Life Sciences at the Wichita State University
1994 Outstanding Researcher of the Year Award, Electrical Engineering Department, Utah State University
1994 State of Utah Governor's Medal for Science and Technology
1996 Honoree, Virginia Polytechnic Institute and State University 75th Anniversary
Celebration of Admission of Women, Generations of Women Leaders
American Physical Society American Chemical Society Division of Bio-inorganic Chemistry Biophysical Society American Society of Biochemistry and Molecular Biology The Protein Society American Institute of Chemists Society of Applied Spectroscopy American Association for the Advancement of Sceince IEEE Engineering in Medicine and Biology
"EXAFS and Resonance Raman Studies of Metalloproteins and Metal Complexes", J.M. Brown, Dissertation Presented to the Dept. Of Chemistry, Princeton University, September, 1978. (Exxon Research Laboratory) "EXAFS Studies of Carbonic Anhydrase and Resonance Raman Spectroscopy of Iron-Sulfur Proteins", V.K. Yachandra,Dissertation presented to the Dept. of Chemistry, Princeton University, June 1982 (University of California, Lawrence Berkeley Laboratory) "An EXAFS study of Copper Proteins and Several Heme Model Complexes", G.L.Woolery, Dissertation presented to the Dept. of Chemistry, Princeton University, February 1983. (Mobile Research Laboratory) The Proximal Histidine in Enzyme Function", M.R. Chance, Dissertation presented to the Dept. of Biochemistry and Biocphysics, University of Pennsylvania, November 1985.(Dept. of Physiology and Biophysics, Albert Einstein College of medicine. "Spectroscopic Studies of Metal-Substituted Hemoblobins",N. Parthasarathi, Dissertation presented to the Dept. of Chemistry, Princeton University, Janauary 1987. (University of Madras, India) "Low Noise, PC Controlled Spectroscopy", M. Harper, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, August 1990. (Matsushita Corporation, Japan) "Electronics for Pulsed Laser Spectroscopy", R. D. Young, Thisis presented to the Dept. of Electrical andC Computer Engineering , Utah State University, August 1990 (Voice, Inc.) "Scientific Visualization", N. Venkateswaran, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, April 1991. (Intel Corporation) "TransAcq: A Transputer-Based Real Time Time-Resolved Data Acquisition and Preliminary Analysis System for Optical Absorption Spectroscopy", B. Duncan, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, April 1991 (Northwest Pipeline Corp.) "X-ray Absorption Studies of the Active Sites of Horseradish Peroxidase, Lactoperoxidase and Their Derivatives", C.S.Chang, Thesis presented to the Dept. of Chemistry and Biochemistry, Utah State University, July 1991. (Martek Bioscience) "Extended X-ray Absorption Fine Structure and Redox Potential Studies of Heme Substituted Horseradish Peroxidase and Myoglobin, Bing He, Thesis presented to the Dept. of Chemistry and Biochemistry, Utah State University, Noveber 1993. (Ph.D. candidate, Purdue University) "Timing Circuitry and Flow Apparatus for Laser Spectroscopy", Shu Chen, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, April 1994. (Vertical Technologies) "Transputer Based Spectrophotometer Detection and Analysis System", Benjamin Kendall, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, April 1994.(Extended Systems, Inc.) "Comparative Biochemistry of Peroxidases", Z.Shadi Farhangrazi, Dissertation presented to the Dept. of Chemistry and Biochemistry , Utah State University, December 1994. (post-doctoral fellow, University of California at Irvine) "Characterization of An Axial Ligand Substitution in Sperm Whale Myoglobin", Michael Chen, Thesis presented to the Dept. of Chemistry and Biochemistry, Utah State University, December 1994.(post-doctoral fellow, University of Mississipi) "Development and Characterization of an Optical Ring-Down Cavity System", Ming Yin, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, June 1995. (Benedict college) "Parallel Stochastic Algorithms for the Analysis of X-ray Absorption Fine Structures [EXAFS] Data", Csaba Gyulai, Dissertation presented to the Dept. of Electrical and Computer Engineering, Utah State University, December 1998. (Visionary Products, Inc.) "Real-Time, Multi-Wavelength Microbe Detection Instrument", Cory R. Estes, Thesis presented to the Dept. of Electrical and Computer Engineering, Utah State University, May 2000.
Method and Apparatus for Sensing the Presence of Microbes, L. Powers. U.S.Patent 5,760,406, June 2 1999 Method and Apparatus for the Taxanomic Identification of Microorganisms, Proteins, and Peptides Involve
in Vertebrate Disease States, L. Powers and W. Ellis, Jr., allowed, filed April 26 1997.Alcohol Breath Analyzer, L. Powers and C. R. Reed, B-E Safe, Inc., in process of filling Sol-Gel Immorbilization of Redox Enzymes for the Synthesis of Fine Chemicals in Supercritical Carbon
Dioxide, W. Ellis, Jr., T.Eyring, C.Lloyd, and L. Powers, in the process of filling.Method and Apparatus for Detecting the Presence of Microbial Cells, Spores, and Proteinaceous Matter
, L. Powers and W. E. Ellis, Jr., in process of filling.
Office Phone: (435)797-2033
Fax: (435)797-3328
E-Mail: lsp@biocat.ncdmf.usu.edu
Office hours (Fall qtr, 1999) TTh 10:30 am - 12:00 noon